Cardiac Veins

The cardiac veins carry deoxygenated blood from the myocardium to the right atrium.

  • Cardiac veins are classified by their blood-flow return to the heart:
    • The coronary sinus (and its four major tributaries) drains into the right atrium.
    • The anterior cardiac veins drain directly into the right atrium.
    • The small cardiac veins drain directly into the nearest chamber.

Pathway of venous return to the coronary sinus:

The coronary sinus is a wide, short vessel that drains directly into the right atrium. It runs in the posterior coronary sulcus.

  • Four major tributaries:
    • Great cardiac vein
    • Left posterior ventricular vein
    • Middle cardiac vein
    • Small cardiac vein

Anterior interventricular vein

  • Arises near the apex of the heart and travels superiorly (within the anterior interventricular sulcus).
  • Once it reaches the coronary sulcus, the anterior interventricular vein becomes the great cardiac vein.
    • Travels posteriorly to drain directly into the left end of the coronary sinus (be aware that some texts do not name the anterior interventricular vein separately; instead, they refer to this entire vessel as the great cardiac vein).

Right marginal vein

  • Travels superiorly along the right side of the heart.
  • At the coronary sulcus, the right marginal vein becomes the small cardiac vein.
    • Wraps posteriorly to drain directly into the right end of the coronary sulcus (in some individuals, the right marginal vein drains directly into the right atrium).

Middle cardiac vein

  • Arises near the apex and runs in the posterior interventricular sulcus (hence, it is also called the posterior interventricular vein).

Left posterior ventricular vein

  • Arises between the great and middle cardiac veins.

Anterior cardiac veins

  • Arise on the superior surface of the right ventricle, and drain directly into the right atrium.

Smallest cardiac veins

aka, venae cordis minimae, aka, thebesian veins

  • Valveless vessels that drain directly into the cardiac chambers, particularly the right atrium.

Vein – Artery Associations:

  • The anterior interventricular vein travels with the anterior interventricular artery.
  • The middle cardiac vein travels with the posterior interventricular artery.
  • The small cardiac vein travels with the right coronary artery.
  • The right marginal vein travels with the right marginal artery.

In Summary:

The great cardiac and left posterior ventricular veins drain regions of the myocardium supplied by the left coronary artery;
The middle and small cardiac veins drain regions of the myocardium supplied by the right coronary artery.

LICHENOID REACTION

🔹 Etiology:

  • Diabetes Mellitus (cell mediated contact hypersensitivity – Type IV)
  • Graft-versus-host disease
  • Drugs
  • Flavouring agents
  • Tobacco chewing

🔹 Drugs:

  • Antimalarials
  • NSAID’s
  • Anti-hypertensives
  • Hypoglycaemics
  • Beta-blockers

🔹 Clinical Features:

➡️ Reticular, erythematous, erosive lesions or ulcerations with whitish streak. Atypical location & absence of bilateral occurrence.

🔹 Histological Features:

  • Inflammatory infiltrate – diffuse & extends deep into lamina propria
  • ⬆️ no. of civatte bodies
  • Perivascular infiltrate seen
  • Lichenoid dysplasia

🔹 Prognosis:

  • Malignant transformation rate – high
  • Months to resolve.

Dr. Mehnaz Memon🖊

References: Shafers Textbook Of Oral Pathology 7Ed

ORAL LESIONS IN HIV INFECTION

🔹 Introduction:

➡️ They are clearly visible & can be easily diagnosed as per the clinical features alone – high viral load. They are useful markers of disease progression & immuno-suppression.

➡️ The EC (1995) gave two diagnostic criterias:

  1. Presumptive (initial clinical appearance)
  2. Definitive (special investigation for diagnosis)

🔹 Classification:

1) Group 1 lesions: (Lesions strongly associated with HIV infection)

🔸 Candidiasis – 4 clinical patterns observed

  1. Pseudomembranous
  2. Erythematous
  3. Hyperplastic
  4. Angular cheilitis

🔸 Hairy Leukoplakia – Associated with EBV

  • Lateral borders of tongue as painless, faint white vertical streaks or thickened & furrowed areas with shaggy keratotic surface – imparting corrugated appearance.
  • Homosexual males
  • Basal epithelial cells – harbour EBV (Latent)

⬇️

Langerhan cells by HIV

⬇️

cause reactivation of EBV

⬇️

epithelial hyperplasia

  • Histological Features:
  1. Acanthosis, hyperkeratosis
  2. Balloon cells – upper prickle layer
  3. Epithelial cells show Nuclear beading

🔸 Kaposis’s Sarcoma (HHV-8)

🔸 Non-hodgkin’s lymphoma

🔸 Periodontal Disease

  • Linear Gingival Erythema
  • NUG
  • NUP

2) Group 2 Lesions: (Less Common)

🔸 Bacterial infection

  • Mycobacterium TB
  • Mycobacterium avium

🔸 HSV, Herpes Zoster

🔸 Melanotic hyperpigmentation (Brown-black intra-oral focal/diffuse Macules)

🔸 Necrotizing Ulcerative Stomatitis

3) Group 3: (Lesions associated with HIV infection)

Dr. Mehnaz Memon🖊


References: Ghom’s Oral medicine & Internet