Pathogenesis of Staph. aureus

Staph aureus | Neuros- Social Networking For Medical Students ...

What is Staphylococcous ?

A gram positive cocci and that is arranged in grape like clusters. They mainly cause suppuration

The important species of Staphylococcus are –

  • Staph.aureus
  • Staph.epidermidis
  • Staph.saprophyticus
Staphylococcus epidermidis - Wikipedia
staph.epidermidis
Staphylococcus Saprophyticus - Stock Image - B234/0182 - Science ...
staph . saprophyticus
Difference Between Staphylococcus Epidermidis and Staphylococcus ...

Staphylococcus aureus

  • They are gram positive cocci
  • Arranged in grape like clusters
  • They are non motile,non sporing
  • Diameter – 1 micrometer approx.
  • Grow in culture medium between 10-42 degree celcius but approximately at 37 degrees celcius
  • Grow at a pH of 7.4-7.6
  • They are aerobes and facultative anaerobes (which can also grow without oxygen)
Staphylococcus aureus (S .aureus) | SnackSafely.com
staph. aureus

Pathogenesis

  • It is a very important pyogenic organism and lesions are localized in nature.
  • They produce thick cream colored colonies

They are classified as –

  • cutaneous and deep infections
  • nosocomial infections
  • food poisoning
  • skin exfoliative diseases
  • toxic shock syndrome

1.Cutaneous infecctions – superficial infecctions

  • pustules
Pustule: Causes, Symptoms, Diagnosis, Treatment and Prevention
  • boils
Boils: Pictures on Skin, Causes, and Treatment
  • carbuncles
Carbuncles: Treatment, pictures, causes and symptoms - TODAY
  • impetigo
Impetigo - Wikipedia
  • pemphigus neonatrum
Pemphigus - Symptoms and causes - Mayo Clinic
  • styes
Stye Symptoms and Treatment in Children
  • abscesses
Abscess - NHS
  • wound and burn infections
Treatment of Infection in Burn Patients - ScienceDirect

2. Deep infections

  • osteomyelitis
  • tonsillitis
  • pharyngitis
  • pneumonitis
  • endocarditis
  • empyema
  • bacteremia
  • septicemia
  • meningitis
  • sinusitis
The role of nasal carriage in Staphylococcus aureus infections ...

3. Food poisoning –

Staphylococcal food poisoning may follow 2-6 hrs after injestion of contaminated food that has preformed entertoxin.

Food Poisoning: Tummy Trouble | BusinessMirror

4.Nosocomial infections –

They are important cause of hospital acquired infections

5.Skin exfoliative Diseases

  • These are produced by strains of Staph.aureus .
  • There is stripping of the superficial layers of skin from the underlying tissue .
  • They are Ritters disease ,pemphigous neonatrum,bullous impetigo.
  • Staphylococcocal scaled skin syndrome (SSSS) is the example. In this the toxin is spread systemically.
Nepal STAPHYLOCOCCUS n Staphylococcus causes diseases ranging from ...

6. Toxic shock syndrome –

  • It is caused by TSST-1 ( toxic shock syndrome toxin ). This is characterised by high fever,hypotension, diarrhoea, scarletiniform rash,vomiting.
emDOCs.net – Emergency Medicine EducationStaphylococcal toxic ...
  • It is also associated with use of tampons by mentruating women which is rare.
Toxic shock syndrome is rare. Be vigilant but not alarmed

source – C P Baveja textbook of microbiology for dental students and google images