Clotting mechanism – Enzyme cascade theory

Clotting – It is defined as the process in which blood looses it’s fluidity and becomes a jelly like substance few minutes after it is shed out.

Sequence of clotting mechanism – Enzyme cascade theory:

Cascade is a process that occurs through a series of steps , each step initiating the next until the final step is reached.

Stages of blood clotting :

  • Formation of prothrombin activator
  • Conversion of prothrombin into thrombin
  • Conversion of fibrinogen into fibrin

Sources – Sembulingam (Textbook of physiology)

Image source – Google images