In recent years, there has been a growing interest in the development of in-office bleaching gels containing co-doped titanium dioxide nanoparticles. Titanium dioxide (TiO2) nanoparticles have been widely studied and utilized in various applications due to their unique properties, such as high refractive index and photocatalytic activity (Kury et al., 2022). The incorporation of TiO2 nanoparticles into bleaching gels has been shown to enhance the effectiveness and safety of the bleaching process.

One study investigated the use of in-office bleaching gels containing high concentrations of hydrogen peroxide (HP) and co-doped titanium dioxide nanoparticles (Kury et al., 2022). The results showed that the incorporation of titanium dioxide nanoparticles into the bleaching gels improved their effectiveness in tooth bleaching. The photocatalytic activity of the nanoparticles enhanced the bleaching process by accelerating the chemical reaction of the hydrogen peroxide. This study highlights the potential of co-doped titanium dioxide nanoparticles in improving the performance of in-office bleaching gels.

Another study evaluated the effect of light irradiation on the bleaching process using a low-concentration hydrogen peroxide solution containing titanium dioxide as a photocatalyst (Suemori et al., 2008). The results showed that light irradiation significantly enhanced the bleaching effect of the hydrogen peroxide solution. The photocatalytic activity of titanium dioxide nanoparticles under light irradiation played a crucial role in accelerating the bleaching process. This study further supports the use of titanium dioxide nanoparticles as a photocatalyst in in-office bleaching gels.

Furthermore, the safety of in-office bleaching gels containing titanium dioxide nanoparticles has been investigated. One study evaluated a low-concentration hydrogen peroxide experimental bleaching gel containing titanium dioxide and chitosan (Ozcetin & Surmelioglu, 2020). The results showed that the gel was safe and effective for tooth bleaching. The presence of titanium dioxide nanoparticles in the gel contributed to its safety and effectiveness. This study provides evidence for the safety of in-office bleaching gels containing titanium dioxide nanoparticles.

In addition to titanium dioxide, other dopants have been explored to enhance the properties of titanium dioxide nanoparticles. For example, iron-doped titanium dioxide nanoparticles have been synthesized and studied for various applications (Abza et al., 2022). The doping of titanium dioxide with iron can modify its properties and enhance its photocatalytic activity. This suggests that co-doping titanium dioxide nanoparticles with other elements may further improve the performance of in-office bleaching gels.

Overall, the incorporation of co-doped titanium dioxide nanoparticles into in-office bleaching gels shows promise in improving the effectiveness and safety of the bleaching process. The photocatalytic activity of titanium dioxide nanoparticles enhances the bleaching process by accelerating the chemical reaction of hydrogen peroxide. Furthermore, the safety of in-office bleaching gels containing titanium dioxide nanoparticles has been demonstrated. Further research on the co-doping of titanium dioxide nanoparticles with other elements may lead to even more effective bleaching gels.

Abza, T., Saka, A., Jule, L., Gudata, L., Nagaprasad, N., & Ramaswamy, K. (2022). Synthesis and characterization of iron doped titanium dioxide (fe: tio2) nanoprecipitate at different ph values for applications of self-cleaning materials. Advances in Materials Science and Engineering, 2022, 1-9. https://doi.org/10.1155/2022/2748908 Kury, M., Hiers, R., Zhao, Y., Picolo, M., Hsieh, J., Khajotia, S., … & Cavalli, V. (2022). Novel experimental in-office bleaching gels containing co-doped titanium dioxide nanoparticles. Nanomaterials, 12(17), 2995. https://doi.org/10.3390/nano12172995 Ozcetin, H. and Surmelioglu, D. (2020). three‐month evaluation of a low concentration (6% hydrogen peroxide) experimental bleaching gel containing tio 2 and chitosan: an in vitro study. Color Research & Application, 45(6), 1101-1108. https://doi.org/10.1002/col.22543 Suemori, T., Kato, J., Nakazawa, T., Akashi, G., Igarashi, A., Hirai, Y., … & Kurata, H. (2008). Effects of light irradiation on bleaching by a 3.5% hydrogen peroxide solution containing titanium dioxide. Laser Physics Letters, 5(5), 379-383. https://doi.org/10.1002/lapl.200710137