Gene Expression Regulation Overview

  • Allows organisms to be more efficient with resources and to adapt to the environment
  • Important for cell differentiation (which results in many different cell types)

STEPS REGULATION OCCURS

  1. Transcriptional Control
  • When and how often a gene is transcribed
  • Only point where the cell will not synthesize unneeded intermediates, thereby wasting resources
  1. RNA Processing Control
  • Control of the splicing and processing of RNA transcripts
  1. RNA Transport and Localization Control
  • Cells select which mRNAs are exported to the cytoplasm and where they are localized to
  1. Translational Control
  • Control which mRNAs get translated into protein
  1. mRNA Degradation Control
  • Cells can destabilize specific mRNAs in the cytoplasm to limit protein production
  1. Protein Activity Control
  • Cells can selectively activate, inactivate, localize or degrade proteins after they have been synthesized

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