GLUCOSE OXIDATION EQUATION
Glucose + 6 O2 –> 6 CO2 + 6 H2O + Energy (ATP + heat)

• Most energy is generated in mitochondrial matrix

Common Abbreviations:

• ATP: adenosine triphosphate
• NADH: nicotinamide adenine dinucleotide
• FADH2: flavin adenine dinucleotide
• CoA: Coenzyme A

KEY PROCESSES IN GLUCOSE OXIDATION

• Glycolysis
• Pyruvate decarboxylation
• Citric acid cycle (also known as the Krebs’ cycle and the tri-carboxylic acid (TCA) cycle)
• Oxidative phosphorylation (electron transport chain & chemiosmosis)

GLYCOLYSIS

• 1 glucose –> 2 pyruvate + 2 ATP + 2 NADH
• Anaerobic reaction: no O2 required
• Occurs in cytosol

Substrate level phosphorylation

• ATP generated from substrates in glycolysis and citric acid cycle
• NOT from oxidative phosphorylation via NADH or FADH2

PYRUVATE DECARBOXYLATION

• Pyruvate + CoA + NAD+ –> Acetyl-CoA + CO2 + NADH
• Occurs in mitochondrial matrix