1. Causative Organisms
2. Predisposing Procedures
3. Predisposing Conditions

Let’s read about causative organisms that cause endocarditis

1. Less Virulent: Streptococcus
   • virdans
   • mitis
   • bovis
2. Highly Virulent
   • Staphylococcus aureus
   • Gonorrhoea
   • Pseudomonas
   • Streptococcus pneumonia
3. Coagulase-negative staphylococci
4. Gram-Negative HACEK
   • Haemophilus
   • Actinobacillus
   • Cardiobacterium
   • Eikenalla
   • Kingella
5. Bartonella (responsible for the high number of culture-negative endocarditis cases)
6. Fungus, moulds, yeasts- cause endocarditis in immunosuppressive patients.

Let’s read about predisposing procedures!

• Respiratory infection
• Obstetric delivery
• Dental procedures (including routine tooth cleaning)
• Genitourinary procedures
• Skin infections
• Prosthetic Valve Recipient
• Cardiac Surgery
• Biliary duct surgery
• Cystic surgery in females

Let’s talk about predisposing conditions

• High-Risk Group
  • Prosthetic valves
  • Surgically constructed AV shunts
  • Complex valve surgery
• Moderate Risk Group
  • Mitral valve collapse
  • Mitral regurgitation
  • Hypertrophic myocardiopathy
• Low-Risk Group
  • Coronary atrial bypass
  • Intracardial placement