Author: Charu Lata

Aplastic anemia

Charu LataLeave a comment
Fanconi’s anemia
  • A. Normal bone marrow B. Aplastic bone marrow
Bone marrow changes
Thrombocytopenia in aplastic anemia
Oral manifestations
Diagnosis and treatment

Sources : Shafer’s textbook of oral pathology , slideshare.com

Image sources : Slideshare and Google images

Plummer Vinson syndrome

Charu LataLeave a comment

Plummer Vinson triad :

  • Postcricoid dysphagia
  • Upper esophageal webs
  • Iron deficiency anemia

High risk of “squamous cell carcinoma”

Risk factors :

  • Race – White and Scandinavian
  • Age – 40-70 years
  • Sex – Females more than males. Especially in postmenopausal women.

Pathophysiology :

  • Iron deficiency anemia
  • Nutritional deficiency
  • Genetic predisposition
  • Autoimmunity causes may include rheumatoid arthritis , pernicious anemia and thyroiditis.

Signs :

  • Angular cheilitis
  • Glossitis (Atrophic bald tongue)
  • Pallor – Palmer pallor and conjunctival pallor
  • Platynychia (Flattened nails)
  • Koilonychia (Spoon shaped nails)
  • Splenomegaly
  • Edentia (loss of teeth due to esophageal reflux)
  • Enlarged nodular thyroid gland
  • Gastritis with acholorhydia
  • Post cricoid webs
  • Picca
  • Beeturia
  • Restless leg syndrome

Symptoms :

  • Dysphagia
  • Odynophagia
  • Choking spells and aspiration due to proximal location of webs
  • Weakness and fatigue
  • Weight loss
  • Hair loss
Treatment

References – Shafer’s textbook of oral pathology , SN Chugh – Textbook of clinical medicine for dental students , slideshare.com

Image reference : Google images.

Thalassemia 2

Charu LataLeave a comment
Clinical features and oral manifestations.
Rodent / Chipmunk face
Laboratory and radiological findings.
Target cells.
Rib within rib appearance
Crew cut / hair on end appearance
Salt and pepper effect
Electrophoresis and treatment

References – Shafer’s Oral pathology , S.N chugh – Textbook of clinical medicine for dental students

Image source – Google images.

Happy reading 🙂