- Stage 1 – Initial stage
- Starts at 2 – 4 days after beginning of plaque accumulation
- Increase vascularity
- Increase GCF flow
- Stage of subclinical gingivitis = no clinical changes
- Immune cells = PMNs are main line of defense
- Important feature = increase in GCF flow
- Stage 2 – Early stage
- Early lesion evolves from initial lesion 4 – 7 days after the beginning of plaque accumulation
- Clinical signs appear in this stage
- BOP
- Erythema
- Important feature = clinical signs appear
- Immune cells = lymphocytes
- Collagen destruction increases
- 70% of collagen fibers are affected
- Main fiber groups involved
- Circular
- Dentogingival
- Stage 3 – Established lesion
- Severely inflamed gingiva/chronic gingivitis
- It occurs for 14 – 21 days after the beginning of plaque accumulation
- Immune cells = Plasma cells
- Important feature = change in color, size, texture
- Bluish hue on the reddened gingiva
- Blood flow sluggish
- Impaired venous return
- Stage 4 – Advanced lesion
- Gingivitis progresses to periodontitis
- CT loss
- Gingivitis is T-cell lesion
- Periodontitis is B cell lesion
- When gingivitis is dominated by T cells = Contained gingivitis
- Term subclinical gingivitis was coined by LINDHE, synonym of stage 1
- Number of transmigrating leukocytes and amount of GCF = between 6 to 12 days of gingivitis = these values become maximum
