By Dr Musaddika Shaikh Dentowesome @drmusaddikashaikh
Plasma proteins :- They are also know as blood proteins. They are proteins which are present in blood plasma
Constituents :-
Origin :-
- Embryo from Mesenchymal cell
- Adult albumin from liver
- Globulin from tissue, macrophages,plasma cells, lymphocytes
Types :-
- Albumin :- 1.control collodial osmotic pressure 2.transport anion,cation,drugs,hormones,enzymes,billirubin
- Globulin :- regulate iron absorption and transport
- Fibrinogen :- helps in clotting
- Hepatoglobin :- prevent loss of iron in urinary excretion
Variation in plasma concentration :- Decrease – haemorrhage causes loss of plasma protein. Fibrinogen, albumin,globulin are regenerated by restoration effect in few days. Decrease of albumin causes during pregnancy,chronic liver disease, malnutrition,fasting, malabsorption,burn,nephrosis. Increase – loss due to burn or dehydration
Functions :-
- Helps in coagulation of blood
- Helps in maintaining colloidal osmotic pressure by urea,Na+,glucose
- Helps in maintaining Hydrostatic Pressure across cavity wall
- Helps in maintaining viscosity of blood
- Helps in Hypoproteinemia
- Helps in immune function
Reference :- Book Human physiology for bds A.K Jain Google website studyblue.com, Philadelphia.edu.jo
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