- Dental lamina cyst of Newborn
- Gingival cyst of Newborn
- Epstein’s pearls, Bohn’s nodules

Dental lamina cyst of newborn are multiple, occasionally solitary, superficial raised nodules on edentulous alveolar ridges of infants that resolve without treatment; derived from rests of dental lamina & consisting of keratin producing epithelial lining.
Cystic keratin filled nodules; derived from epithelial remnants entrapped along line of fusion, usually seen at midpalatine raphe.
Keratin filled cysts scattered over the palate at the junction of hard and soft palate; derived from palatal salivary gland structures.
🔹Introduction:
- A special form of odontogenic cyst – 80% of the infants.
- Gingival cyst is M/E similar to epidermoid cyst.
- It develops after 4 week in utero.
- Palatal Cyst arises from epithelial remnants in stroma after fusion of palatal processes usually at posterior midline of hard palate.
🔹Clinical Features:
➡️ Gingival Cyst:
- They are multiple, superficial raised nodules on edentulous alveolar ridge of infants that resolve without treatment.
- They are localized in corium below the surface epithelium.
- Those found in anterior portion of jaw are displaced lingually & in posterior portion are found occlusal to crown of molars.
- They are asymptomatic and do not produce any discomfort to the infant.
- These are small discrete, white swellings, blanched from internal pressure.
➡️ Palatal Cyst:
- They are Multiple (<6), 1-4mm in size & yellow-white in color. Sessile mucosal papules of posterior hard palate.
- They are larger & less numerous than gingival cyst. Both are so superficial that several may be ruptured at the time of examination.
🔹 Histopathological Features:
- Thin, stratified squamous epithelium – produce keratin.
- Fibrovascular connective tissue stroma without inflammatory infilterate.
- Cystic lumen filled with degenerated keratin, formed into concentric layers/onion rings.
- Epithelium lacks Rete processes.
- Dystrophic calcification & Hyaline bodies seen.
🔹Treatment:
Generally self limiting, (within 3 months) no treatment is required in most of the cases. If baby is having feeding difficulties, complete excision of the cyst can be done.
References: Shafer’s Textbook of Oral Pathology 7th Edition
Dr. Mehnaz Memon🖊
